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Selective Targeting of Tumour Necrosis Factor Receptor 1 Induces Stable Protection from Crohn’s-Like Ileitis in TNF(ΔARE) Mice

BACKGROUND AND AIMS: Crohn’s disease is a debilitating chronic inflammatory disorder of the mammalian gastrointestinal tract. Current interventions using anti-tumour necrosis factor [anti-TNF] biologics show long-term benefit in only half of patients. This study focused on the role of the TNF recept...

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Detalles Bibliográficos
Autores principales: Chakraborty, Rajrupa, Maltz, Mia R, Del Castillo, Diana, Tandel, Purvi N, Messih, Nathalie, Anguiano, Martha, Lo, David D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282884/
https://www.ncbi.nlm.nih.gov/pubmed/34893805
http://dx.doi.org/10.1093/ecco-jcc/jjab222