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Selective Targeting of Tumour Necrosis Factor Receptor 1 Induces Stable Protection from Crohn’s-Like Ileitis in TNF(ΔARE) Mice
BACKGROUND AND AIMS: Crohn’s disease is a debilitating chronic inflammatory disorder of the mammalian gastrointestinal tract. Current interventions using anti-tumour necrosis factor [anti-TNF] biologics show long-term benefit in only half of patients. This study focused on the role of the TNF recept...
Autores principales: | Chakraborty, Rajrupa, Maltz, Mia R, Del Castillo, Diana, Tandel, Purvi N, Messih, Nathalie, Anguiano, Martha, Lo, David D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282884/ https://www.ncbi.nlm.nih.gov/pubmed/34893805 http://dx.doi.org/10.1093/ecco-jcc/jjab222 |
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