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High D-glucose levels induce ACE2 expression via GLUT1 in human airway epithelial cell line Calu-3

BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters the host cell by binding to angiotensin-converting enzyme 2 (ACE2) receptors. ACE2 is expressed on human airway epithelial cells. Increased ACE2 expression may be associated with potentially high risk of COVID-19. Howeve...

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Detalles Bibliográficos
Autores principales: Wakabayashi, Yoshitaka, Nakayama, Shin, Yamamoto, Ai, Kitazawa, Takatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282902/
https://www.ncbi.nlm.nih.gov/pubmed/35836103
http://dx.doi.org/10.1186/s12860-022-00427-4