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A Shigella species variant is causally linked to intractable functional constipation

Intractable functional constipation (IFC) is the most severe form of constipation, but its etiology has long been unknown. We hypothesized that IFC is caused by refractory infection by a pathogenic bacterium. Here, we isolated from patients with IFC a Shigella species — peristaltic contraction–inhib...

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Detalles Bibliográficos
Autores principales: Chen, Xin, Qiu, Tian-Tian, Wang, Ye, Xu, Li-Yang, Sun, Jie, Jiang, Zhi-Hui, Zhao, Wei, Tao, Tao, Zhou, Yu-Wei, Wei, Li-Sha, Li, Ye-Qiong, Zheng, Yan-Yan, Zhou, Guo-Hua, Chen, Hua-Qun, Zhang, Jian, Feng, Xiao-Bo, Wang, Fang-Yu, Li, Ning, Zhang, Xue-Na, Jiang, Jun, Zhu, Min-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282927/
https://www.ncbi.nlm.nih.gov/pubmed/35617029
http://dx.doi.org/10.1172/JCI150097