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A Shigella species variant is causally linked to intractable functional constipation
Intractable functional constipation (IFC) is the most severe form of constipation, but its etiology has long been unknown. We hypothesized that IFC is caused by refractory infection by a pathogenic bacterium. Here, we isolated from patients with IFC a Shigella species — peristaltic contraction–inhib...
Autores principales: | Chen, Xin, Qiu, Tian-Tian, Wang, Ye, Xu, Li-Yang, Sun, Jie, Jiang, Zhi-Hui, Zhao, Wei, Tao, Tao, Zhou, Yu-Wei, Wei, Li-Sha, Li, Ye-Qiong, Zheng, Yan-Yan, Zhou, Guo-Hua, Chen, Hua-Qun, Zhang, Jian, Feng, Xiao-Bo, Wang, Fang-Yu, Li, Ning, Zhang, Xue-Na, Jiang, Jun, Zhu, Min-Sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282927/ https://www.ncbi.nlm.nih.gov/pubmed/35617029 http://dx.doi.org/10.1172/JCI150097 |
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