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Distinct histopathological phenotypes of severe alcoholic hepatitis suggest different mechanisms driving liver injury and failure

Intrahepatic neutrophil infiltration has been implicated in severe alcoholic hepatitis (SAH) pathogenesis; however, the mechanism underlying neutrophil-induced injury in SAH remains obscure. This translational study aims to describe the patterns of intrahepatic neutrophil infiltration and its involv...

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Detalles Bibliográficos
Autores principales: Ma, Jing, Guillot, Adrien, Yang, Zhihong, Mackowiak, Bryan, Hwang, Seonghwan, Park, Ogyi, Peiffer, Brandon J., Ahmadi, Ali Reza, Melo, Luma, Kusumanchi, Praveen, Huda, Nazmul, Saxena, Romil, He, Yong, Guan, Yukun, Feng, Dechun, Sancho-Bru, Pau, Zang, Mengwei, Cameron, Andrew MacGregor, Bataller, Ramon, Tacke, Frank, Sun, Zhaoli, Liangpunsakul, Suthat, Gao, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282929/
https://www.ncbi.nlm.nih.gov/pubmed/35838051
http://dx.doi.org/10.1172/JCI157780