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Prospectively defined patterns of APOBEC3A mutagenesis are prevalent in human cancers
Mutational signatures defined by single base substitution (SBS) patterns in cancer have elucidated potential mutagenic processes that contribute to malignancy. Two prevalent mutational patterns in human cancers are attributed to the APOBEC3 cytidine deaminase enzymes. Among the seven human APOBEC3 p...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283007/ https://www.ncbi.nlm.nih.gov/pubmed/35320711 http://dx.doi.org/10.1016/j.celrep.2022.110555 |