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Prospectively defined patterns of APOBEC3A mutagenesis are prevalent in human cancers

Mutational signatures defined by single base substitution (SBS) patterns in cancer have elucidated potential mutagenic processes that contribute to malignancy. Two prevalent mutational patterns in human cancers are attributed to the APOBEC3 cytidine deaminase enzymes. Among the seven human APOBEC3 p...

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Detalles Bibliográficos
Autores principales:	DeWeerd, Rachel A., Németh, Eszter, Póti, Ádám, Petryk, Nataliya, Chen, Chun-Long, Hyrien, Olivier, Szüts, Dávid, Green, Abby M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283007/ https://www.ncbi.nlm.nih.gov/pubmed/35320711 http://dx.doi.org/10.1016/j.celrep.2022.110555

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