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Paxlovid: Mechanism of Action, Synthesis, and In Silico Study

In this work, the discovery and description of PF-07321332, a major bioavailable oral SARS-CoV-2 protease inhibitor with in vitro human coronavirus antiviral activity, and excellent selection of off-target and in vivo immune profiles are reported. Various drugs and novel compound candidates for the...

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Detalles Bibliográficos
Autores principales: Marzi, Mahrokh, Vakil, Mohammad Kazem, Bahmanyar, Maryam, Zarenezhad, Elham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283023/
https://www.ncbi.nlm.nih.gov/pubmed/35845944
http://dx.doi.org/10.1155/2022/7341493