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Human cytosolic transaminases: side activities and patterns of discrimination towards physiologically available alternative substrates

Transaminases play key roles in central metabolism, transferring the amino group from a donor substrate to an acceptor. These enzymes can often act, with low efficiency, on compounds different from the preferred substrates. To understand what might have shaped the substrate specificity of this class...

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Detalles Bibliográficos
Autores principales: Caligiore, Francesco, Zangelmi, Erika, Vetro, Carola, Kentache, Takfarinas, Dewulf, Joseph P., Veiga-da-Cunha, Maria, Van Schaftingen, Emile, Bommer, Guido, Peracchi, Alessio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283133/
https://www.ncbi.nlm.nih.gov/pubmed/35834009
http://dx.doi.org/10.1007/s00018-022-04439-3