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Human cytosolic transaminases: side activities and patterns of discrimination towards physiologically available alternative substrates
Transaminases play key roles in central metabolism, transferring the amino group from a donor substrate to an acceptor. These enzymes can often act, with low efficiency, on compounds different from the preferred substrates. To understand what might have shaped the substrate specificity of this class...
Autores principales: | Caligiore, Francesco, Zangelmi, Erika, Vetro, Carola, Kentache, Takfarinas, Dewulf, Joseph P., Veiga-da-Cunha, Maria, Van Schaftingen, Emile, Bommer, Guido, Peracchi, Alessio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283133/ https://www.ncbi.nlm.nih.gov/pubmed/35834009 http://dx.doi.org/10.1007/s00018-022-04439-3 |
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