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Lessons from single-cell RNA sequencing of human islets

Islet dysfunction is central in type 2 diabetes and full-blown type 2 diabetes develops first when the beta cells lose their ability to secrete adequate amounts of insulin in response to raised plasma glucose. Several mechanisms behind beta cell dysfunction have been put forward but many important q...

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Detalles Bibliográficos
Autores principales: Ngara, Mtakai, Wierup, Nils
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283180/
https://www.ncbi.nlm.nih.gov/pubmed/35482056
http://dx.doi.org/10.1007/s00125-022-05699-1