Novel insight into the role of clusterin on intraocular pressure regulation by modifying actin polymerization and extracellular matrix remodeling in the trabecular meshwork

This study provides comprehensive mechanistic evidence for the role of clusterin, a stress‐response secretory chaperone protein, in the modulation of intraocular pressure (IOP) by regulating the trabecular meshwork (TM) actin cytoskeleton and the extracellular matrix (ECM). The pathological stressor...

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Detalles Bibliográficos
Autores principales: Soundararajan, Avinash, Wang, Ting, Ghag, Sachin A., Kang, Min H., Pattabiraman, Padmanabhan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283260/
https://www.ncbi.nlm.nih.gov/pubmed/35567755
http://dx.doi.org/10.1002/jcp.30769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283260/
https://www.ncbi.nlm.nih.gov/pubmed/35567755
http://dx.doi.org/10.1002/jcp.30769

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