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Novel insight into the role of clusterin on intraocular pressure regulation by modifying actin polymerization and extracellular matrix remodeling in the trabecular meshwork
This study provides comprehensive mechanistic evidence for the role of clusterin, a stress‐response secretory chaperone protein, in the modulation of intraocular pressure (IOP) by regulating the trabecular meshwork (TM) actin cytoskeleton and the extracellular matrix (ECM). The pathological stressor...
Autores principales: | Soundararajan, Avinash, Wang, Ting, Ghag, Sachin A., Kang, Min H., Pattabiraman, Padmanabhan P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283260/ https://www.ncbi.nlm.nih.gov/pubmed/35567755 http://dx.doi.org/10.1002/jcp.30769 |
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