Reappraisal of the Medical Research Council Antiepileptic Drug Withdrawal Study: Contamination‐adjusted and dose‐response re‐analysis

OBJECTIVE: The 1991 Medical Research Council (MRC) Study compared seizure relapse for seizure‐free patients randomized to withdraw vs continue of antiseizure medications (ASMs). We re‐analyzed this trial to account for crossover between arms using contamination‐adjusted intention to treat (CA ITT) m...

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Detalles Bibliográficos
Autores principales: Terman, Samuel W., Wang, Chang, Wang, Lu, Braun, Kees P. J., Otte, Willem M., Slinger, Geertruida, Kerr, Wesley T., Lossius, Morten I., Bonnett, Laura, Burke, James F., Marson, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283317/
https://www.ncbi.nlm.nih.gov/pubmed/35490396
http://dx.doi.org/10.1111/epi.17273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283317/
https://www.ncbi.nlm.nih.gov/pubmed/35490396
http://dx.doi.org/10.1111/epi.17273

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