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Unraveling the therapeutic potential of GANT61/Dactolisib combination as a novel prostate cancer modality

Aberrant activation of several signaling pathways has been implicated in prostate cancer (PCa) progression to castrate-resistant prostate cancer (CRPC). Phosphoinositide-3-kinase/Protein Kinase B/mechanistic Target of Rapamycin (PI3K/AKT/mTOR) and Hedgehog/GLI (Hh/GLI) pathways are major participant...

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Detalles Bibliográficos
Autores principales: Youssef, Mohamed, Moussa, Nermine, W. Helmy, Maged, Haroun, Medhat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283339/
https://www.ncbi.nlm.nih.gov/pubmed/35834137
http://dx.doi.org/10.1007/s12032-022-01718-8