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On the microstructurally driven heterogeneous response of brain white matter to drug infusion pressure

Delivering therapeutic agents into the brain via convection-enhanced delivery (CED), a mechanically controlled infusion method, provides an efficient approach to bypass the blood–brain barrier and deliver drugs directly to the targeted focus in the brain. Mathematical methods based on Darcy’s law ha...

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Detalles Bibliográficos
Autores principales: Yuan, Tian, Zhan, Wenbo, Jamal, Asad, Dini, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283367/
https://www.ncbi.nlm.nih.gov/pubmed/35717548
http://dx.doi.org/10.1007/s10237-022-01592-3