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Semaphorin 5A suppresses ferroptosis through activation of PI3K-AKT-mTOR signaling in rheumatoid arthritis

Abnormal activation of synovial fibroblasts (SFs) plays an important role in rheumatoid arthritis (RA), the mechanism of which remains unknown. The purpose of our study is to comprehensively and systematically explore the mechanism for Semaphorin 5A-mediated abnormal SF activation in RA. Here, we fo...

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Detalles Bibliográficos
Autores principales: Cheng, Qi, Chen, Mo, Liu, Mengdan, Chen, Xin, Zhu, Lingjiang, Xu, Jieying, Xue, Jing, Wu, Huaxiang, Du, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283415/
https://www.ncbi.nlm.nih.gov/pubmed/35835748
http://dx.doi.org/10.1038/s41419-022-05065-4