Adipocyte lysoplasmalogenase TMEM86A regulates plasmalogen homeostasis and protein kinase A-dependent energy metabolism

Dysregulation of adipose tissue plasmalogen metabolism is associated with obesity-related metabolic diseases. We report that feeding mice a high-fat diet reduces adipose tissue lysoplasmalogen levels and increases transmembrane protein 86 A (TMEM86A), a putative lysoplasmalogenase. Untargeted lipido...

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Detalles Bibliográficos
Autores principales: Cho, Yoon Keun, Yoon, Young Cheol, Im, Hyeonyeong, Son, Yeonho, Kim, Minsu, Saha, Abhirup, Choi, Cheoljun, Lee, Jaewon, Lee, Sumin, Kim, Jae Hyun, Kang, Yun Pyo, Jung, Young-Suk, Ha, Hong Koo, Seong, Je Kyung, Granneman, James G., Kwon, Sung Won, Lee, Yun-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283435/
https://www.ncbi.nlm.nih.gov/pubmed/35835749
http://dx.doi.org/10.1038/s41467-022-31805-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283435/
https://www.ncbi.nlm.nih.gov/pubmed/35835749
http://dx.doi.org/10.1038/s41467-022-31805-3

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