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A rationally identified panel of microRNAs targets multiple oncogenic pathways to enhance chemotherapeutic effects in glioblastoma models

Glioblastoma (GBM) is the most common malignant brain tumor. Available treatments have limited success because most patients develop chemoresistance. Alternative strategies are required to improve anticancer effects of current chemotherapeutics while limiting resistance. Successful targeting of micr...

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Detalles Bibliográficos
Autores principales: Sadeghipour, Negar, Kumar, Sukumar Uday, Massoud, Tarik F., Paulmurugan, Ramasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283442/
https://www.ncbi.nlm.nih.gov/pubmed/35835978
http://dx.doi.org/10.1038/s41598-022-16219-x