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Structures of β(1)-adrenergic receptor in complex with Gs and ligands of different efficacies
G-protein-coupled receptors (GPCRs) receive signals from ligands with different efficacies, and transduce to heterotrimeric G-proteins to generate different degrees of physiological responses. Previous studies revealed how ligands with different efficacies activate GPCRs. Here, we investigate how a...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283524/ https://www.ncbi.nlm.nih.gov/pubmed/35835792 http://dx.doi.org/10.1038/s41467-022-31823-1 |