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Structures of β(1)-adrenergic receptor in complex with Gs and ligands of different efficacies

G-protein-coupled receptors (GPCRs) receive signals from ligands with different efficacies, and transduce to heterotrimeric G-proteins to generate different degrees of physiological responses. Previous studies revealed how ligands with different efficacies activate GPCRs. Here, we investigate how a...

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Detalles Bibliográficos
Autores principales:	Su, Minfei, Paknejad, Navid, Zhu, Lan, Wang, Jinan, Do, Hung Nguyen, Miao, Yinglong, Liu, Wei, Hite, Richard K., Huang, Xin-Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283524/ https://www.ncbi.nlm.nih.gov/pubmed/35835792 http://dx.doi.org/10.1038/s41467-022-31823-1

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