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TIGIT Deficiency Protects Mice From DSS-Induced Colitis by Regulating IL-17A–Producing CD4(+) Tissue-Resident Memory T Cells

Tissue-resident memory T cells (T(RM) cells) have been shown to play an instrumental role in providing local immune responses for pathogen clearance in barrier tissues. However, their contribution to inflammatory bowel diseases (IBDs) and the underlying regulation are less clear. Here, we identified...

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Detalles Bibliográficos
Autores principales: Chen, Binfeng, Ye, Baokui, Li, Mengyuan, Wang, Shuyi, Li, Jin, Lai, Yimei, Yang, Niansheng, Ke, Zunfu, Zhang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283574/
https://www.ncbi.nlm.nih.gov/pubmed/35844584
http://dx.doi.org/10.3389/fimmu.2022.931761