Identification of Selective CYP3A7 and CYP3A4 Substrates and Inhibitors Using a High-Throughput Screening Platform

Cytochrome P450 (CYP) 3A7 is one of the major xenobiotic metabolizing enzymes in human embryonic, fetal, and newborn liver. CYP3A7 expression has also been observed in a subset of the adult population, including pregnant women, as well as in various cancer patients. The characterization of CYP3A7 is...

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Detalles Bibliográficos
Autores principales: Kabir, Md, Padilha, Elias C., Shah, Pranav, Huang, Ruili, Sakamuru, Srilatha, Gonzalez, Eric, Ye, Lin, Hu, Xin, Henderson, Mark J., Xia, Menghang, Xu, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283723/
https://www.ncbi.nlm.nih.gov/pubmed/35847040
http://dx.doi.org/10.3389/fphar.2022.899536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283723/
https://www.ncbi.nlm.nih.gov/pubmed/35847040
http://dx.doi.org/10.3389/fphar.2022.899536

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