5FU/Oxaliplatin-Induced Jagged1 Cleavage Counteracts Apoptosis Induction in Colorectal Cancer: A Novel Mechanism of Intrinsic Drug Resistance

Colorectal cancer (CRC) is characterized by early metastasis, resistance to anti-cancer therapy, and high mortality rate. Despite considerable progress in the development of new treatment options that improved survival benefits in patients with early-stage or advanced CRC, many patients relapse due...

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Detalles Bibliográficos
Autores principales: Pelullo, Maria, Zema, Sabrina, De Carolis, Mariangela, Cialfi, Samantha, Giuli, Maria Valeria, Palermo, Rocco, Capalbo, Carlo, Giannini, Giuseppe, Screpanti, Isabella, Checquolo, Saula, Bellavia, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283835/
https://www.ncbi.nlm.nih.gov/pubmed/35847908
http://dx.doi.org/10.3389/fonc.2022.918763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283835/
https://www.ncbi.nlm.nih.gov/pubmed/35847908
http://dx.doi.org/10.3389/fonc.2022.918763

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