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The SARS‐CoV‐2 main protease (M(pro)): Structure, function, and emerging therapies for COVID‐19

The main proteases (M(pro)), also termed 3‐chymotrypsin‐like proteases (3CL(pro)), are a class of highly conserved cysteine hydrolases in β‐coronaviruses. Increasing evidence has demonstrated that 3CL(pro)s play an indispensable role in viral replication and have been recognized as key targets for p...

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Detalles Bibliográficos
Autores principales: Hu, Qing, Xiong, Yuan, Zhu, Guang‐Hao, Zhang, Ya‐Ni, Zhang, Yi‐Wen, Huang, Ping, Ge, Guang‐Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283855/
https://www.ncbi.nlm.nih.gov/pubmed/35845352
http://dx.doi.org/10.1002/mco2.151