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Ablation of PI3K-p110alpha Impairs Maternal Metabolic Adaptations to Pregnancy

Pregnancy requires adaptations in maternal metabolism to support fetal growth. The phosphoinositol-3-kinase (PI3K) signalling pathway controls multiple biological processes and defects in this pathway are linked to metabolic disorders including insulin resistance and glucose intolerance in non-pregn...

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Detalles Bibliográficos
Autores principales: Lopez-Tello, Jorge, Salazar-Petres, Esteban, Webb, Liam, Fowden, Abigail L., Sferruzzi-Perri, Amanda N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283861/
https://www.ncbi.nlm.nih.gov/pubmed/35846351
http://dx.doi.org/10.3389/fcell.2022.928210