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β-Adrenergic Receptor Desensitization/Down-Regulation in Heart Failure: A Friend or Foe?

Cardiac sympathetic activation, mediated by β-adrenergic receptors (β-ARs), normally increases cardiac contraction and relaxation. Accomplishing this task requires a physiological, concerted Ca(2+) signaling, being able to increase Ca(2+) release from sarcoplasmic reticulum (SR) in systole and speed...

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Detalles Bibliográficos
Autores principales:	Mahmood, Abrahim, Ahmed, Kinza, Zhang, Youhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283919/ https://www.ncbi.nlm.nih.gov/pubmed/35845057 http://dx.doi.org/10.3389/fcvm.2022.925692

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