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Recent insights into noncanonical 5′ capping and decapping of RNA

The 5′ N(7)-methylguanosine cap is a critical modification for mRNAs and many other RNAs in eukaryotic cells. Recent studies have uncovered an RNA 5′ capping quality surveillance mechanism, with DXO/Rai1 decapping enzymes removing incomplete caps and enabling the degradation of the RNAs, in a proces...

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Detalles Bibliográficos
Autores principales: Doamekpor, Selom K., Sharma, Sunny, Kiledjian, Megerditch, Tong, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283932/
https://www.ncbi.nlm.nih.gov/pubmed/35750211
http://dx.doi.org/10.1016/j.jbc.2022.102171