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Characterization of a [4Fe-4S]-dependent LarE sulfur insertase that facilitates nickel-pincer nucleotide cofactor biosynthesis in Thermotoga maritima

Sulfur-insertion reactions are essential for the biosynthesis of several cellular metabolites, including enzyme cofactors. In Lactobacillus plantarum, a sulfur-containing nickel-pincer nucleotide (NPN) cofactor is used as a coenzyme of lactic acid racemase, LarA. During NPN biosynthesis in L. planta...

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Detalles Bibliográficos
Autores principales: Chatterjee, Shramana, Parson, Kristine F., Ruotolo, Brandon T., McCracken, John, Hu, Jian, Hausinger, Robert P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283937/
https://www.ncbi.nlm.nih.gov/pubmed/35700827
http://dx.doi.org/10.1016/j.jbc.2022.102131