Coming full circle: On the origin and evolution of the looping model for enhancer–promoter communication

In mammalian organisms, enhancers can regulate transcription from great genomic distances. How enhancers affect distal gene expression has been a major question in the field of gene regulation. One model to explain how enhancers communicate with their target promoters, the chromatin looping model, p...

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Detalles Bibliográficos
Autores principales: Popay, Tessa M., Dixon, Jesse R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283939/
https://www.ncbi.nlm.nih.gov/pubmed/35691341
http://dx.doi.org/10.1016/j.jbc.2022.102117