Coming full circle: On the origin and evolution of the looping model for enhancer–promoter communication
In mammalian organisms, enhancers can regulate transcription from great genomic distances. How enhancers affect distal gene expression has been a major question in the field of gene regulation. One model to explain how enhancers communicate with their target promoters, the chromatin looping model, p...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283939/ https://www.ncbi.nlm.nih.gov/pubmed/35691341 http://dx.doi.org/10.1016/j.jbc.2022.102117 |