Identification and functional implications of pseudouridine RNA modification on small noncoding RNAs in the mammalian pathogen Trypanosoma brucei

Trypanosoma brucei, the parasite that causes sleeping sickness, cycles between an insect and a mammalian host. However, the effect of RNA modifications such as pseudouridinylation on its ability to survive in these two different host environments is unclear. Here, two genome-wide approaches were app...

Descripción completa

Detalles Bibliográficos
Autores principales: Rajan, K. Shanmugha, Adler, Katerina, Doniger, Tirza, Cohen-Chalamish, Smadar, Aharon-Hefetz, Noa, Aryal, Saurav, Pilpel, Yitzhak, Tschudi, Christian, Unger, Ron, Michaeli, Shulamit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283944/
https://www.ncbi.nlm.nih.gov/pubmed/35714765
http://dx.doi.org/10.1016/j.jbc.2022.102141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283944/
https://www.ncbi.nlm.nih.gov/pubmed/35714765
http://dx.doi.org/10.1016/j.jbc.2022.102141

Ejemplares similares