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Measurement of autophagy via LC3 western blotting following DNA-damage-induced senescence
Senescent cells accumulation is associated with aging and age-related diseases, and recent findings suggest that autophagy, the activity of the intracellular degradation system, decreases during senescence. In this protocol, we detail steps to induce cellular senescence in response to DNA damage, ev...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283947/ https://www.ncbi.nlm.nih.gov/pubmed/35819884 http://dx.doi.org/10.1016/j.xpro.2022.101539 |