Intrathecal sc-AAV9-CB-GFP: Systemic Distribution Predominates Following Single-Dose Administration in Cynomolgus Macaques

Biodistribution of self-complementary adeno-associated virus-9 (scAAV9)–chicken β-actin promoter–green fluorescent protein (GFP) was assessed in juvenile cynomolgus macaques infused intrathecally via lumbar puncture or the intracisterna magna (1.0×10(13) or 3.0×10(13) vg/animal), with necropsy 28 da...

Descripción completa

Detalles Bibliográficos
Autores principales: Meseck, Emily K., Guibinga, Ghiabe, Wang, Stephen, McElroy, Cameron, Hudry, Eloise, Mansfield, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284083/
https://www.ncbi.nlm.nih.gov/pubmed/35658751
http://dx.doi.org/10.1177/01926233221101309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284083/
https://www.ncbi.nlm.nih.gov/pubmed/35658751
http://dx.doi.org/10.1177/01926233221101309

Ejemplares similares