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Regulation of Nucleotide Metabolism with Nutrient‐Sensing Nanodrugs for Cancer Therapy

The continual growth of tumor cells requires considerable nutrient consumption. Methotrexate (MTX) is used to treat certain types of cancer by blocking the DNA and RNA productions through interfering one‐carbon metabolism and de novo purine and pyrimidine synthesis. However, treatment of MTX may cau...

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Detalles Bibliográficos
Autores principales: Wang, Xinye, Su, Wen, Jiang, Yongbin, Jia, Fuhao, Huang, Wenping, Zhang, Jie, Yin, Yue, Wang, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284143/
https://www.ncbi.nlm.nih.gov/pubmed/35508896
http://dx.doi.org/10.1002/advs.202200482