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Regulation of Nucleotide Metabolism with Nutrient‐Sensing Nanodrugs for Cancer Therapy
The continual growth of tumor cells requires considerable nutrient consumption. Methotrexate (MTX) is used to treat certain types of cancer by blocking the DNA and RNA productions through interfering one‐carbon metabolism and de novo purine and pyrimidine synthesis. However, treatment of MTX may cau...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284143/ https://www.ncbi.nlm.nih.gov/pubmed/35508896 http://dx.doi.org/10.1002/advs.202200482 |