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Targeting mTORC2/HDAC3 Inhibits Stemness of Liver Cancer Cells Against Glutamine Starvation

Cancer cells are addicted to glutamine. However, cancer cells often suffer from glutamine starvation, which largely results from the fast growth of cancer cells and the insufficient vascularization in the interior of cancer tissues. Herein, based on clinical samples, patient‐derived cells (PDCs), an...

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Detalles Bibliográficos
Autores principales: Zhang, Hui‐Lu, Chen, Ping, Yan, He‐Xin, Fu, Gong‐Bo, Luo, Fei‐Fei, Zhang, Jun, Zhao, Shi‐Min, Zhai, Bo, Yu, Jiang‐Hong, Chen, Lin, Cui, Hao‐Shu, Chen, Jian, Huang, Shuai, Zeng, Jun, Xu, Wei, Wang, Hong‐Yang, Liu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284171/
https://www.ncbi.nlm.nih.gov/pubmed/35187863
http://dx.doi.org/10.1002/advs.202103887