BLM Sumoylation Is Required for Replication Stability and Normal Fork Velocity During DNA Replication

BLM is sumoylated in response to replication stress. We have studied the role of BLM sumoylation in physiologically normal and replication-stressed conditions by expressing in BLM-deficient cells a BLM with SUMO acceptor-site mutations, which we refer to as SUMO-mutant BLM cells. SUMO-mutant BLM cel...

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Detalles Bibliográficos
Autores principales: de Renty, Christelle, Pond, Kelvin W., Yagle, Mary K., Ellis, Nathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284272/
https://www.ncbi.nlm.nih.gov/pubmed/35847987
http://dx.doi.org/10.3389/fmolb.2022.875102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284272/
https://www.ncbi.nlm.nih.gov/pubmed/35847987
http://dx.doi.org/10.3389/fmolb.2022.875102

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