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BLM Sumoylation Is Required for Replication Stability and Normal Fork Velocity During DNA Replication
BLM is sumoylated in response to replication stress. We have studied the role of BLM sumoylation in physiologically normal and replication-stressed conditions by expressing in BLM-deficient cells a BLM with SUMO acceptor-site mutations, which we refer to as SUMO-mutant BLM cells. SUMO-mutant BLM cel...
Autores principales: | de Renty, Christelle, Pond, Kelvin W., Yagle, Mary K., Ellis, Nathan A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284272/ https://www.ncbi.nlm.nih.gov/pubmed/35847987 http://dx.doi.org/10.3389/fmolb.2022.875102 |
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