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4″-Sulfation Is the Major Metabolic Pathway of Epigallocatechin-3-gallate in Humans: Characterization of Metabolites, Enzymatic Analysis, and Pharmacokinetic Profiling

[Image: see text] Epigallocatechin-3-gallate (EGCG), a major green tea polyphenol, has beneficial effects on human health. This study aimed to elucidate the detailed EGCG sulfation process to better understand its phase II metabolism, a process required to maximize its health benefits. Results show...

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Detalles Bibliográficos
Autores principales: Hayashi, Akane, Terasaka, Shimpei, Nukada, Yuko, Kameyama, Akiyo, Yamane, Masayuki, Shioi, Ryuta, Iwashita, Masazumi, Hashizume, Kohjiro, Morita, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284555/
https://www.ncbi.nlm.nih.gov/pubmed/35786898
http://dx.doi.org/10.1021/acs.jafc.2c02150