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Chronic upper airway inflammation related to high Th2 cytokines in Mendelian susceptibility to mycobacterial disease case

In this report, we have described a child suffering from Mendelian susceptibility to mycobacterial disease (MSMD) owing to an autosomal recessive, complete T-bet deficiency, which impairs IFN-γ production by innate and innate-like adaptive, but not mycobacterial-reactive purely adaptive lymphocytes....

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Detalles Bibliográficos
Autores principales: Benhsaien, Ibtihal, Yang, Rui, Ailal, Fatima, Weisshaar, Marc, Mele, Federico, Casanova, Jean-Laurent, Bustamante, Jacinta, Bousfiha, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: HBKU Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284602/
https://www.ncbi.nlm.nih.gov/pubmed/35909394
http://dx.doi.org/10.5339/qmj.2022.fqac.24