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Effects of SPA4 peptide on lipopolysaccharide‐disrupted lung epithelial barrier, injury, and function in a human cell system and mouse model of lung injury

Disrupted epithelial barrier, fluid accumulation, inflammation, and compromised physiology are hallmarks of lung injury. Here we investigated the structural stability of the Toll‐like receptor‐4 (TLR4)‐interacting SPA4 peptide, its effect on Pseudomonas aeruginosa lipopolysaccharide (LPS)‐disrupted...

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Detalles Bibliográficos
Autores principales: Chowdhury, Asif Alam, Godbole, Nachiket M., Chataut, Neha, Kosanke, Stanley, Rodgers, Karla, Awasthi, Shanjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284632/
https://www.ncbi.nlm.nih.gov/pubmed/35838161
http://dx.doi.org/10.14814/phy2.15353