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Silencing of Nesprin‐2 inhibits the differentiation of myofibroblasts from fibroblasts induced by mechanical stretch

Mechanical force plays a pivotal role in the pathogenesis of hypertrophic scar (HTS). Dermal fibroblasts and myofibroblasts are the key cells involved in HTS. Myofibroblasts in HTS possess different biochemical and biophysical characteristics by which myofibroblasts are often distinguished from fibr...

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Detalles Bibliográficos
Autores principales: Xu, Quanchen, Miao, Yuanxin, Ren, Jizheng, Sun, Yu, Li, Cong, Cai, Xia, Wang, Zhiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284660/
https://www.ncbi.nlm.nih.gov/pubmed/34558192
http://dx.doi.org/10.1111/iwj.13694