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Anti-fibrotic effect of a selective estrogen receptor modulator in systemic sclerosis

BACKGROUND: The rarity of systemic sclerosis (SSc) has hampered the development of therapies for this intractable autoimmune disease. Induced pluripotent stem cell (iPSC) can be differentiated into the key disease-affected cells in vitro. The generation of patient-derived iPSCs has opened up possibi...

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Detalles Bibliográficos
Autores principales: Kim, Yena, Nam, Yoojun, Rim, Yeri Alice, Ju, Ji Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284699/
https://www.ncbi.nlm.nih.gov/pubmed/35841004
http://dx.doi.org/10.1186/s13287-022-02987-w