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UC-MSCs promote frozen-thawed ovaries angiogenesis via activation of the Wnt/β-catenin pathway in vitro ovarian culture system

BACKGROUND: Ovarian tissue cryopreservation and transplantation are novel therapeutic approaches for fertility preservation. However, follicle loss caused by ischemic and hypoxic damage is one of the issues after frozen-thawed ovarian tissue transplantation. Promoting angiogenesis in grafts is the k...

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Detalles Bibliográficos
Autores principales: Xu, Wenjuan, Wu, Caiyun, Zhu, Xiaoqian, Wu, Jingjing, Zhang, Zhiguo, Wei, Zhaolian, Cao, Yunxia, Zhou, Ping, Wang, Jianye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284710/
https://www.ncbi.nlm.nih.gov/pubmed/35841074
http://dx.doi.org/10.1186/s13287-022-02989-8