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Exosomal lncRNA TUG1 derived from human urine-derived stem cells attenuates renal ischemia/reperfusion injury by interacting with SRSF1 to regulate ASCL4-mediated ferroptosis

BACKGROUND: Human urine-derived stem cells (USCs)-derived exosomes (USC-Exo) could improve kidney ischemia/reperfusion injury (IRI), while the underlying mechanisms of this protective effect remain unclear. METHODS: Human USCs and USC-Exo were isolated and verified by morphology and specific biomark...

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Detalles Bibliográficos
Autores principales: Sun, Zejia, Wu, Jiyue, Bi, Qing, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284726/
https://www.ncbi.nlm.nih.gov/pubmed/35841017
http://dx.doi.org/10.1186/s13287-022-02986-x