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PDIA3P1 promotes Temozolomide resistance in glioblastoma by inhibiting C/EBPβ degradation to facilitate proneural-to-mesenchymal transition

BACKGROUND: Resistance to temozolomide (TMZ) is a major obstacle to preventing glioblastoma (GBM) recurrence after surgery. Although long noncoding RNAs (lncRNAs) play a variety of roles in GBM, the lncRNAs that regulate TMZ resistance have not yet been clearly elucidated. This study aims to identif...

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Detalles Bibliográficos
Autores principales: Gao, Zijie, Xu, Jianye, Fan, Yang, Qi, Yanhua, Wang, Shaobo, Zhao, Shulin, Guo, Xing, Xue, Hao, Deng, Lin, Zhao, Rongrong, Sun, Chong, Zhang, Ping, Li, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284800/
https://www.ncbi.nlm.nih.gov/pubmed/35836243
http://dx.doi.org/10.1186/s13046-022-02431-0