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Diverse actions of sirtuin-1 on ovulatory genes and cell death pathways in human granulosa cells

BACKGROUND: Human granulosa-lutein cells (hGLCs) amply express sirtuin-1 (SIRT1), a NAD + -dependent deacetylase that is associated with various cellular functions. SIRT1 was shown to elevate cAMP on its own and additively with human chorionic gonadotropin (hCG), it is therefore interesting to exami...

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Detalles Bibliográficos
Autores principales: Sapuleni, Jackson, Szymanska, Magdalena, Meidan, Rina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284863/
https://www.ncbi.nlm.nih.gov/pubmed/35840944
http://dx.doi.org/10.1186/s12958-022-00970-x