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Diverse actions of sirtuin-1 on ovulatory genes and cell death pathways in human granulosa cells
BACKGROUND: Human granulosa-lutein cells (hGLCs) amply express sirtuin-1 (SIRT1), a NAD + -dependent deacetylase that is associated with various cellular functions. SIRT1 was shown to elevate cAMP on its own and additively with human chorionic gonadotropin (hCG), it is therefore interesting to exami...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284863/ https://www.ncbi.nlm.nih.gov/pubmed/35840944 http://dx.doi.org/10.1186/s12958-022-00970-x |