CCND1 Amplification Profiling Identifies a Subtype of Melanoma Associated With Poor Survival and an Immunosuppressive Tumor Microenvironment

BACKGROUND: Although melanoma is generally regarded as an immunogenic cancer that will respond to immune checkpoint inhibitors (ICIs), melanomas with CCND1 amplification respond poorly to these therapies. Further understanding how CCND1 amplification impacts the effectiveness of ICI therapy is impor...

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Detalles Bibliográficos
Autores principales: Liu, Jun, Lin, Jing, Wang, Xuefeng, Zheng, Xiaobin, Gao, Xuan, Huang, Yingying, Chen, Gang, Xiong, Jiani, Lan, Bin, Chen, Chuanben, Si, Lu, Chen, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285001/
https://www.ncbi.nlm.nih.gov/pubmed/35844619
http://dx.doi.org/10.3389/fimmu.2022.725679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285001/
https://www.ncbi.nlm.nih.gov/pubmed/35844619
http://dx.doi.org/10.3389/fimmu.2022.725679

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