Cargando…

CCND1 Amplification Profiling Identifies a Subtype of Melanoma Associated With Poor Survival and an Immunosuppressive Tumor Microenvironment

BACKGROUND: Although melanoma is generally regarded as an immunogenic cancer that will respond to immune checkpoint inhibitors (ICIs), melanomas with CCND1 amplification respond poorly to these therapies. Further understanding how CCND1 amplification impacts the effectiveness of ICI therapy is impor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Jun, Lin, Jing, Wang, Xuefeng, Zheng, Xiaobin, Gao, Xuan, Huang, Yingying, Chen, Gang, Xiong, Jiani, Lan, Bin, Chen, Chuanben, Si, Lu, Chen, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285001/ https://www.ncbi.nlm.nih.gov/pubmed/35844619 http://dx.doi.org/10.3389/fimmu.2022.725679

Ejemplares similares

CCND1 Amplification Contributes to Immunosuppression and Is Associated With a Poor Prognosis to Immune Checkpoint Inhibitors in Solid Tumors
por: Chen, Yu, et al.
Publicado: (2020)

CCND1 Amplification in Breast Cancer -associations With Proliferation, Histopathological Grade, Molecular Subtype and Prognosis
por: Valla, Marit, et al.
Publicado: (2022)

Role of PRKDC in cancer initiation, progression, and treatment
por: Chen, Yu, et al.
Publicado: (2021)

Anaplastic multiple myeloma with amplification of the IGH-CCND1 gene fusion
por: Alencar, Rafael Nobrega, et al.
Publicado: (2023)

Poor clinical outcome in metastatic melanoma is associated with a microRNA-modulated immunosuppressive tumor microenvironment
por: Jorge, Natasha A. N., et al.
Publicado: (2020)

Heterogeneity of amplification of HER2, EGFR, CCND1 and MYC in gastric cancer
por: Stahl, Phillip, et al.
Publicado: (2015)

BAFF Attenuates Immunosuppressive Monocytes in the Melanoma Tumor Microenvironment
por: Liu, Wei, et al.
Publicado: (2022)

Oesophageal cancer and amplification of the human cyclin D gene CCND1/PRAD1.
por: Adélaide, J., et al.
Publicado: (1995)

Features of the immunosuppressive tumor microenvironment in endometrial cancer based on molecular subtype
por: Zhang, Chong, et al.
Publicado: (2023)

Pivotal factors associated with the immunosuppressive tumor microenvironment and melanoma metastasis
por: Zhang, Chuan, et al.
Publicado: (2021)

Exosome-Mediated Immunosuppression in Tumor Microenvironments
por: Xie, Qi-Hui, et al.
Publicado: (2022)

GATAD1 gene amplification promotes glioma malignancy by directly regulating CCND1 transcription
por: Zhang, Shanshan, et al.
Publicado: (2019)

High FAAP24 expression reveals poor prognosis and an immunosuppressive microenvironment shaping in AML
por: Bao, Xiebing, et al.
Publicado: (2023)

Genome-Wide Analysis Reveals Hypoxic Microenvironment Is Associated With Immunosuppression in Poor Survival of Stage II/III Colorectal Cancer Patients
por: Chen, Yu-feng, et al.
Publicado: (2021)

New strategies for melanoma immunotherapy: How to overcome immunosuppression in the tumor microenvironment
por: Umansky, Viktor
Publicado: (2012)

Dynamic change in Siglec-15 expression in peritumoral macrophages confers an immunosuppressive microenvironment and poor outcome in glioma
por: Chen, Quan, et al.
Publicado: (2023)

LY2874455 and Abemaciclib Reverse FGF3/4/19/CCND1 Amplification Mediated Gefitinib Resistance in NSCLC
por: Liu, Dongcheng, et al.
Publicado: (2022)

KYNU as a Biomarker of Tumor-Associated Macrophages and Correlates with Immunosuppressive Microenvironment and Poor Prognosis in Gastric Cancer
por: Shen, Kaiyu, et al.
Publicado: (2023)

Amplification of the EGFR and CCND1 Are Coordinated and Play Important Roles in the Progression of Oral Squamous Cell Carcinomas
por: Chien, Huei-Tzu, et al.
Publicado: (2019)

ETNK2 Low-Expression Predicts Poor Prognosis in Renal Cell Carcinoma with Immunosuppressive Tumor Microenvironment
por: Chu, Jian, et al.
Publicado: (2023)

Immune Subtypes in LUAD Identify Novel Tumor Microenvironment Profiles With Prognostic and Therapeutic Implications
por: Wang, Feng, et al.
Publicado: (2022)

Mitochondrial energy metabolism correlates with an immunosuppressive tumor microenvironment and poor prognosis in esophageal squamous cell carcinoma
por: Zhang, Zewei, et al.
Publicado: (2023)

Cell Cycle Regulation by Alternative Polyadenylation of CCND1
por: Wang, Qiong, et al.
Publicado: (2018)

Prediction of CCND1 amplification using plasma DNA as a prognostic marker in oesophageal squamous cell carcinoma
por: Takeshita, H, et al.
Publicado: (2010)

Cyclin D1 overexpression in Algerian breast cancer women: correlation with CCND1 amplification and clinicopathological parameters
por: Mohammedi, Latifa, et al.
Publicado: (2019)

Immunosuppressive Microenvironment in Neuroblastoma
por: Pistoia, Vito, et al.
Publicado: (2013)

Immune Microenvironment in Glioblastoma Subtypes
por: Chen, Zhihong, et al.
Publicado: (2018)

The KRAS-Mutant Consensus Molecular Subtype 3 Reveals an Immunosuppressive Tumor Microenvironment in Colorectal Cancer
por: Tanjak, Pariyada, et al.
Publicado: (2023)

An independent poor-prognosis subtype of hepatocellular carcinoma based on the tumor microenvironment
por: Wang, Junfeng, et al.
Publicado: (2021)

Improved Anti-Tumour Adaptive Immunity Can Overcome the Melanoma Immunosuppressive Tumour Microenvironment
por: Dang, Nana, et al.
Publicado: (2019)

Immunosuppressive activity is attenuated by Astragalus polysaccharides through remodeling the gut microenvironment in melanoma mice
por: Ding, Guiqing, et al.
Publicado: (2021)

Defeating Melanoma Through a Nano-Enabled Revision of Hypoxic and Immunosuppressive Tumor Microenvironment
por: Yang, Wenzhe, et al.
Publicado: (2023)

Gene products of chromosome 11q and their association with CCND1 gene amplification and tamoxifen resistance in premenopausal breast cancer
por: Lundgren, Katja, et al.
Publicado: (2008)

Intercellular Molecular Crosstalk Networks within Invasive and Immunosuppressive Tumor Microenvironment Subtypes Associated with Clinical Outcomes in Four Cancer Types
por: Wei, Jinfen, et al.
Publicado: (2023)

SETD2 variation correlates with tumor mutational burden and MSI along with improved response to immunotherapy
por: Zheng, Xiaobin, et al.
Publicado: (2023)

Antiangiogenic therapy reverses the immunosuppressive breast cancer microenvironment
por: Chen, Wuzhen, et al.
Publicado: (2021)

FXYD3 Expression Predicts Poor Prognosis in Renal Cell Carcinoma with Immunosuppressive Tumor Microenvironment
por: Yonekura, Satoru, et al.
Publicado: (2022)

Overexpression of CHAF1A is associated with poor prognosis, tumor immunosuppressive microenvironment and treatment resistance
por: Sun, Xia, et al.
Publicado: (2023)

Modes of immunosuppression in glioblastoma microenvironment
por: Lehtipuro, Suvi, et al.
Publicado: (2019)

Role of the immunosuppressive microenvironment in immunotherapy
por: Tormoen, Garth W., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_qq9qh7f4i9s7m4vft9h00beu43